近期论文

Zeng HH， Zhang HB*，Synthesis and biological evaluation of fatty acids conjugates bearing cyclopentadienyl-donors incorporated [(99m)Tc/Re(CO)3](+) for myocardical imaging， Eur J Med Chem. 2014，24(72):10-7
Yu HJ, Fang Y, Lu X, Liu YJ, Zhang HB*，Combined 3D-QSAR, Molecular Docking, Molecular Dynamics Simulation, and Binding Free Energy Calculation Studies on the 5-Hydroxy-2H-Pyridazin-3-One Derivatives as HCV NS5B Polymerase Inhibitors, CHEMICAL BIOLOGY & DRUG DESIGN ，2014, 83: 89-105
Zeng HH, Zhao LZ, Hu SY, Liu YJ, Yu HJ, Chen N, Zhang HB*.,Synthesis, characterization and biodistribution of new fatty acids conjugates bearing N,N,N-donors incorporated [(99m)Tc/Re(CO)(3)](+), Dalton Trans.2013, 42(8):2894-901.
Lu X, Zhao LZ, Xue T, Zhang HB*, Technetium-99m- Arg-Arg-Leu(g2), a modified peptide probe targeted to neovascularization in molecular tumor imaging, J BUON. 2013 ;18(4):1074-81.
Hu S, Yu H, Liu Y, Xue T, Zhang H. Insight into the binding model of new antagonists of kappa receptor using docking and molecular dynamics simulation. J Mol Model. 2013，19(8):3087-94.
Zeng HH, Zhang HB, Wu XX, Preliminary studies of a novel cyclopentadienyl tricarbonyl technetium-99m fatty acid derivative for myocardical imaging, JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS ，2013，56(1): 1-5.
Liu YJ, Yu HJ, Zhao, LZ, Zhang HB*, Design and synthesis of new agents for neuronal nicotinic acetylcholine receptor (nAChRs) imaging, NUCLEAR MEDICINE AND BIOLOGY,2013, 40(1): 126-134
Liu YJ, Yu HJ, Zhao, LZ, Zhang HB*,Design and synthesis of new agents for neuronal nicotinic acetylcholine receptor (nAChRs) imaging, NUCLEAR MEDICINE AND BIOLOGY 40(1): 126-134,2013.
Zhao, Lingzhou; Liu, Yongjuan; Hu, Shiyuan; ZhangHB* , 3D-QSAR study of Chk1 kinase inhibitors based on docking, JOURNAL OF MOLECULAR MODELING,2012,18(8): 3669-3694
Chen Na; Liu Chunkai; Zhao Lingzhou, Zhang Huabei*, 3D-QSAR study of multi-target-directed AchE inhibitors based on autodocking, MEDICINAL CHEMISTRY RESEARCH, 21(2): 245-256,2012
Zeng H, Zhang H, Jang F, Zhao L, Zhang J. Molecular Modeling Studies on Benzimidazole Carboxamide Derivatives as PARP-1 Inhibitors Using 3D-QSAR and Docking, Chem Biol Drug Des. 2011,78(3):333-52.
Zeng Huahui; Zhang Huabei，Domestic Advances in Brain, Heart, and Tumor Radioactive Diagnosis Drugs，PROGRESS IN CHEMISTRY，2011，23（7）: 1485-1492
Yang Yang; Zhu Lin; Chen Xiangji，Binding research on flavones as ligands of beta-amyloid aggregates by fluorescence and their 3D-QSAR, docking studies，JOURNAL OF MOLECULAR GRAPHICS & MODELLING ，2010，29( 4): 538-545
Yang Y, Zhu L, Cui MC, Tang RK, Zhang HB* Preparation of classical Re/Tc-99m(CO)(3)(+) and novel Tc-99m(CO)(2)(NO)(2+) cores complexed with flavonol derivatives and their binding characteristics for A beta((1-40)) aggregates，BIOORGANIC & MEDICINAL CHEMISTRY LETTERS，2010， 20（ 17）: 5337-5344
Zeng HH, Zhang HB*，Combined 3D-QSAR modeling and molecular docking study on 1,4-dihydroindeno[1,2-c]pyrazoles as VEGFR-2 kinase inhibitors， JOURNAL OF MOLECULAR GRAPHICS & MODELLING，2010, 29（1）， 54-71， 2010
Cao R, Mi N, Zhang H*. 3D-QSAR study of c-Src kinase inhibitors based on docking.J Mol Model. 2010，16(2):361-75.
Yang Y, Zhang JX, Zhu L, Zhang H* Synthesis, Novel Crystal Structure, and beta-Amyloid Binding Property of Re(I) (tricarbonyl) EHIDA Analogue Bioinorg Chem Appl. 2009:702730.
Cao R, Mi N, Zhang H*.,3D-QSAR study of c-Src kinase inhibitors based on docking.J Mol Model. 2010 Feb;16(2):361-75.
Yang Y, Zhu L, Zhang HB*. Di-tert-butyl 2,2'-[(2-hydroxyethyl)azanediyl] diacetate ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE 2009，65（12）3167-U1248.
Cao R, Zeng H, Zhang H*.，3D-QSAR studies on a series of inhibitors docked into a new homology model of the DNA-PK receptor. Curr. Pharm. Des. 2009; 15(32): 3796-825.
Cao HY, Cao R, Zhang HB*, Zheng XF, Gao DB，Non-nucleoside Inhibitors of NS5B Polymerase Binding to Allosteric Sites: 3D- QSAR and Molecular Docking Studies，Curr. Med. Chem., 2008，15: 1462-77.
Zhang HB*, Hu SP, Zhang YL. Prediction of distribution of neutral, acidic and basic structurally diverse compounds between blood and brain by the nonlinear methodology. Med Chem. 2008 , 4:170-89.
Zhang HB*, Li H, Ma QQ QSAR study of a large set of 3-pyridyl ethers analogues，Journal of Molecular Graphics and Modelling, 2007, 26: 226-235.
Cao HY, Zhang HB*，Zheng XF, Gao DB，3D QSAR studies on a series of potent and high selective inhibitors for three kinases of RTK family，Journal of Molecular Graphics and Modelling, 2007, 26:236-245.
Zhang HB*, Zhang YL, Convenient Nonlinear Model for Predicting the Tissue/Blood Partition Coefficients of Seven Human Tissues of Neutral, Acidic and Basic Structural-Diverse Compounds, J. Med. Chem., 2006，49:, 5815-5829.
Zhou JM, Zhou JH, Zhang HB, et al. Fluoro-substitution effects in deoxyfluoro-D-glucose derivatives: random conformational search and quantum chemical calculation , CARBOHYDRATE RESEARCH, 2006, 341: 2224-2232.
Zhang HB*, A QSAR Study of the Brain/Blood Partition Coefficients on the Basis of pKa Values, QSAR & combinary chemistry, 2006, 25:, 15-24.
Zhang HB*, Li H, Liu CP，CoMFA, CoMSIA and Molecular Hologram QSAR Studies of Novel Neuronal nAChRs Ligands – Open Ring Analogues of 3-pyridyl Ether，J. Chem. Inf. model. 2005, 45: 440-448.
Zhang HB*, Ye HH, Zhang YL , et al.Synthesis, biodistribution and QSAR studies of five Tc-99m labeled novel N3S pseudo-peptide complexes， Med. Chem. Res. 2005, 14: 40-56.
Zhang HB*, A new approach for the tissue-blood partition coefficients of neutral and ionized compounds, J. Chem. Inf. model. 2005, 45:121-127.