近期论文

Yu, M.; Hon, G. C.; Szulwach, K. E.; Song, C.-X.; Zhang, L.; Kim, A.; Li, X.; Dai, Q.; Shen, Y.; Park, B.; Min, J.-H.; Jin, P.*; Ren, B.*; He, C.* Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome. Cell 2012, on-line.
Yi, C.; Chen, B.; Zhang, W.; Jia, G.; Zhang, L.; Li, C. J.; Dinner, A. R.; Yang, C.-G.*; He, C.* Duplex Interrogation by a Direct DNA Repair Protein in Search of Base Damage. Nat. Struct. Mol. Biol. 2012, on-line.
Zhang, L.; Lu, X.Y.; Lu, J.Y.; Liang, H.H.; Dai, Q.; Xu, G.L.; Luo, C.; Jiang, H.L.; He, C. Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat. Chem. Biol. 2012, 8, 328-330.
Jia, G.; Fu, Y.; Zhao, X.; Dai, Q.; Zheng, G.; Yang, Y.; Yi, C.; Lindahl, T.; Yang, Y.-G.; He, C.* “N6-methyladesosine in nuclear RNA is a major substrate of the obesity-associated FTO” Nature Chem. Biol. 2011, 7, 885-887.
Qian, Y.; Karpus, J.; Kabil, O.; Zhang, S.-Y.; Zhu, H.-L.; Banerjee, R.; Zhao, J.; He, C.* “Selective fluorescent probes for live-cell monitoring of sulfide” Nature Commun. 2011, 2, 495.
He, Y.; Li, B.; Li, Z.; Liu, P.; Wang, Y.; Tang, Q.; Ding, J.; Jia, Y.; Chen, Z.; Li, L.; Sun, Y.; Li, X.; Dai, Q.; Song, C.-X.; Zhang, K.; He, C.; Xu, G.* “Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA” Science, 2011, 333, 1303-1307.
Ito, S.; Shen, L.; Dai, Q.; Wu, S. C.; Collins, L. B.; Swenberg, J. A.; He, C.; Zhang, Y.* “Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine” Science, 2011, 333, 1300-1303.
Song, C.-X.; Szulwach, K. E.; Fu, Y.; Dai, Q.; Yi, C.; Li, X.; Chen, C.-H.; Zhang, W.; Jian, X.; Wang, J.; Zhang, L.; Looney, T. J.; Zhang, B.; Godley, L. A.; Hicks, L. M.; Lahn, B. T.; Jin, P.*; He, C*. “Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine” Nature Biotechnol., 2011, 29, 68-72.
Yi, C.; Jia, G; Hou, G.; Dai, Q.; Zhang, W.; Zheng, G.; Jian, X.; Yang, C.-G.; Cui, Q.; He, C.* “Iron-catalysed Oxidation Intermediates Captured in a DNA Repair Dioxygenase” Nature, 2010, 468, 330-333.
Yang, C.-G.; Yi, C.; Duguid, E. M.; Sullivan, C. T.; Jian, X.; Rice, P. A.; He, C.* “Crystal Structures of DNA-RNA Repair Enzymes AlkB and ABH2 Bound to dsDNA” Nature, 2008, 452, 961-965.
Chen, P.; Bae, T.; Williams, W. A.; Duguid, E. M.; Rice, P. A.; Schneewind, O.; He, C.* “An Oxidation Sensing Mechanism is Used by A Global Regulator of Staphylococcus aureus” Nature Chem. Biol. 2006, 2, 591-595.
Chen, H.; Hu, J.; Chen, P. R.; Lan, L.; Li, Z.; Hicks, L. M.; Dinner, A. R.; He, C.* “The Pseudomonas aeruginosa Multidrug Efflux Regulator MexR Uses An Oxidation Sensing Mechanism” Proc. Natl. Acad. Sci. 2008, 105, 13586-13591.