个人简历

1998-date School of Life & Health Sciences, Aston University.
1997-98 Post-doctoral Research Fellow, MRC Toxicology Unit, University of Leicester.
1995-96 Post-doctoral Research Assistant, UCL.
1991-95 PhD Student/Research Assistant, UCL.
1990-91 Research Assistant, UCL.
1987-90 Zhejiang University, Zhejiang, China.
1984-87 Zhejiang University, Zhejiang, China, MSc in organic chemistry.
1978-82. Zhejiang University, Zhejiang, China, BSc in chemistry.

近期论文

Y.– Z. Xu, Q. Zheng and P. F. Swann Tetrahedron Letters 32 2817-2820 (1991) Simple synthesis of 4-thiothymidine, 4-thiouridine and 6-thio-2’-deoxyguanosine.
Y. – Z. Xu, Q. Zheng and P. F. Swann Tetrahedron Letters 33 5837-5840 (1992) Synthesis and duplex stability of oligodeoxynucleotides containing 6-mercaptopurine.
Y. – Z. Xu, Q. Zheng and P. F. Swann Tetrahedron 48 1729-1742 (1992) Synthesis by post-synthetic substitution of oligomers containing guanine modified at the 6-position with S-, N-, O-derivatives.
Y. – Z. Xu, Q. Zheng and P. F. Swann Journal of Organic Chemistry 57 3839-3845 (1992) Synthesis of DNA containing modified bases by post-synthetic substitution: Synthesis of oligomers containing 4-substituted thymine: O4-alkylthymine, 5-methylcytosine, N4-dimethylamino-5-methylcytosine and 4-thiothymine.
Y. – Z. Xu, Q. Zheng and P. F. Swann Nucleosides & Nucleosides 14 929-932 (1995) Preparation of oligodeoxynucleotides containing 6-methylthiopurine residues by chemical synthesis or specific methylation
Q. Zheng, Y. – Z. Xu and P. F. Swann Nucleosides & Nucleosides 14 939-942 (1995) An improved post-synthetic substitution approach for synthesis of DNA containing labile 4-substituted thymine.
P. F. Swann, T. R. Waters, D. C. Moulton, Y.- Z. Xu, Q. Zheng, M. Edwards and R. Mace Science 273 1109-1111 (1996) Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.
Y.– Z. Xu, Q. Zheng and P. F. Swann Nucleosides & Nucleosides 16 1559-1562 (1997) Site-specific introduction of functional groups onto bases in synthetic oligonucleotides for biological applications.
Q. Zheng, Y.– Z. Xu and P. F. Swann Nucleosides & Nucleosides 16 1799-1803 (1997) Photochemical cross-linking of l–Cro repressor to operator DNA specifically substituted with 4-thiothymine or 6-thioquanine
M. D. Evans, M. S. Cooke, I. D. Podmore, Q. Zheng, K. E. Herbert, and J. Lunec Biochemical and Biophysical Research Communications 259 374-378 (1999) Discrepancies in the measurement of UVC-induced 8-oxo-2’-deoxyguanosine: Implication of the analysis of oxidative DNA damage.
J. Lunec, K.E. Herbert, G.D.D. Jones, L. Dickinson, M. Evans, N. Mistry, D.Chauhan, G. Capper and Q. Zheng Free Radical Research, 33: 27-31 (2000) Development of a quality control material for the measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine, an In Vivo marker of oxidative stress, and comparison of results from different laboratories.
L. Wang, Z.-C. Chen, Q. Zheng Chinese Journal of Chemistry221457-1459 (2002) Hyperiodine in synthesis 64: Synthesis of diaryl selenides and alkyl aryl selenides by palladium-catalyzed arylation of areneselenyl or alkaneselenyl magnesium bromide with diaryliodonium salt.
D.-P. Cheng, Z.-C. Chen, Q. Zheng J. Chem. Res. 2002: 624-625(2002) Hypervalent iodine in synthesis 91: A mild and efficient method for the halogenation of 6-methyluracil derivatives.
Y.-Y. Xie, Z.-C. Chen, Q. Zheng J. Chem. Res. 2002: 618-619(2002) Organic reactions in ionic liquids: a-tosyloxylation of ketones.
Y-Y Xie, Z-C Chen, Q Zheng Synthesis-Stuttgart 11 1505 -1508 (2002) Organic reactions in ionic liquids: ionic-liquid-accelerated cyclocondensation of a tosyloxyketones with 2-aminopyridine.
C. Su, Z.-C. Chen, Q. Zheng Synthetic Communications 33, 2817-2822 (2003) Organic reactions in ionic liquids: alkylation of Meldrum acid.
D-P Cheng, Z.-C. Chen, Q. Zheng Synthetic Communications 33, 2671-2676 (2003) Hypervalent iodine in synthesis 90: A mild and efficient method for the iodination of pyrazoles.
Z Liu, Z-C Chen, Q, Zheng Org Lett 5 3321-3323 (2003) Mild oxidation of alcohols with O-iodoxybenzoic acid (IBX) in ionic liquid 1-butyl-3-methyl-imidazolium chloride and water.
D-H. Yang, Z-C. Chen, S-Y Chen, Q Zheng Synthesis-Stuttgart 12 1891-1894 (2003) Organic reactions in ionic liquids; Ionic liquid-accelerated three-component reaction: A rapid one-pot synthesis of 3-alkyl-5-[(Z)-arylmethylidene]-1,3-thiazolidine-2,4-diones.
D-H. Yang, Z-C. Chen & Q. Zheng J. Chem. Res. 2003 330-331 (2003) A convenient synthesis of 5-benzylidenethiazolidine-2, 4-diones under microwave irradiation without solvent.