个人简历

学习与工作经历
2012年6月毕业于北京化工大学化学工程与技术专业，获工学博士学位；
2012年7月加入中国石油大学（华东）化学工程学院生物工程与技术中心，任职讲师；
2013年12月破格晋升副教授，硕士生导师。
课题组成员
近年来已指导硕士研究生8名，协助指导博士研究生2名。
已毕业研究生：
1. 孙明彬，2013级，生物工程专业，硕士毕业，在校期间发表SCI论文2篇，获“社会奖学金”，工作单位：药明康德（上海），工程师。
2. 徐燕，2015级，化学工程与技术专业，博士毕业，已发表SCI论文19篇，其中一区论文5篇，第一作者发表论文7篇。2017年、2018年连续两年获得学校“学术十杰”提名奖，获2017年度“国家奖学金”。工作单位：山东科技大学，讲师。
3. 骆珍，2016级，生物化工专业，硕士毕业，已发表SCI论文12篇，其中第一作者发表SCI一区论文2篇，获得2018年度学校“学术十杰”提名奖，获2018年度“国家奖学金”，2017年度“社会奖学金”。单位：浙江大学,读博。
在读研究生：
1. 李世新，2017级，化学工程与技术专业，博士在读，已发表SCI论文21篇，其中第一作者发表论文7篇。
2. 阎增帅，2017级，生物化工专业，硕士在读，已发表SCI论文7篇，其中第一作者发表SCI一区TOP论文1篇，二区TOP论文1篇。
3. 吕汝婕，2018级，生物工程专业，硕士在读，已发表SCI论文1篇。
4. 李灵芝，2019级，生物化工专业，硕士在读。
5. 冯浩，2019级，生物工程专业，硕士在读。
6. 张晓阳，2019级，生物工程专业，硕士在读。
本课题组的研究领域具有显著的学科交叉特点，注重分子模拟与实验的结合，欢迎具有化学、化工、生物、物理、环境、力学、数学或计算机等背景的同学报考！

承担科研课题
国家自然科学基金青年项目（2014-2016）
国家自然科学基金面上项目（2019-2022）
山东省科技重大专项（2016-2018）
山东省自然科学基金青年项目（2013-2015）
山东省自然科学基金面上项目（2018-2020）
青岛市科技计划项目（2013-2015）
青岛市应用基础研究项目（2016-2018）
青年骨干教师建设项目（2014-2018）
国家重点实验室开放课题（2018-2019）
校人才培育项目（2019-2021）
校自主创新项目（2013-2015；2016-2018）

荣誉称号
“青岛市自然科学奖”（2018年）
“青年骨干教师”（2014年）
“北京市优秀博士毕业生”（2012年）
“校级优秀博士学位论文”（2012年）

研究领域

环境纳米毒理；
细胞内吞的分子机制；
重要蛋白质的结构与功能；
细胞的跨膜信号转导机制；
生命软物质的自组织行为；
仿生抗冻材料的设计；
天然气水合物的纳米仿生抑制剂的分子设计及优化。""

近期论文

参与撰写英文专著1部：
1. Falin Tian, Tongtao Yue, Ye Li, Xianren Zhang. Simulations on cell uptake of nanoparticles: membrane-mediated interaction, internalization pathways, and cooperative effect, chapter 8 in Self-assembling systems: theory and simulation. John Wiley & Sons: Oxford, UK. 2016. ISBN: 978-1-119-11314-0.

◎论文
目前主要从事纳米生物学领域的分子模拟与实验研究。近年来先后在ACS Nano、Biomaterials、Journal of Physical Chemistry Letter、ACS Applied Materials & Interfaces、Nanoscale、Environmental Science-Nano、Biophysical Journal、Soft Matter等国际一流学术期刊上发表SCI论文50余 篇，累计被引用次数700余次。代表性论文如下（带*为通讯作者）：

2019年：
1. Yan Xu, Shixin Li, Zengshuai Yan, Baosheng Ge, Fang Huang, Tongtao Yue*. Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations. Journal of Physical Chemistry Letter, 2019, 10, 5815. (SCI一区)
2. Yuchi Liu, Shixin Li, Xuejuan Liu, Hainan Sun, Tongtao Yue*, Xianren Zhang, Bing Yan*, Dapeng Cao*. Design of Small Nanoparticles Decorated with Amphiphilic Ligands: Self-preservation Effect and Translocation into a Plasma Membrane. ACS Applied Materials & Interfaces, 2019, 11, 23822. (SCI一区)
3. Zengshuai Yan, Zeming Wu, Shixin Li, Xianren Zhang, Xin Yi*, Tongtao Yue*. Curvature-mediated cooperative wrapping of multiple nanoparticles at the same and opposite membrane sides. Nanoscale, DOI: 10.1039/C9NR03554K. (SCI一区, selected as “Front Cover”)
4. Tongtao Yue, Hongyu Zhou, Hainan Sun, Shixin Li, Xianren Zhang, Dapeng Cao, Xin Yi*, Bing Yan*. Why nanoparticles are trapped at cell junctions when cell density is high?. Nanoscale, 2019, 11, 6602. (SCI一区, selected as “2019 Nanoscale HOT ARTICLE”)
5. Xinli Gao, Song Hong, Zhiping Liu, Tongtao Yue*, Jure Dobnikar*, Xianren Zhang. Membrane potential drives direct translocation of cell-penetrating peptides. Nanoscale, 2019, 11, 1949. (SCI一区)
6. Shixin Li, Zengshuai Yan, Zhen Luo, Yan Xu, Fang Huang, Xianren Zhang, Xin Yi*, Tongtao Yue*. Mechanics of the Formation, Interaction and Evolution of Membrane Tubular Structures. Biophysical Journal, 2019, 116, 884. (SCI二区, selected as “Video Highlighted Featured Article”).
7. Ye Li, Xianren Zhang, Jinxing Lin, Ruili Li*, Tongtao Yue*. Extracting lipid vesicles from plasma membranes via self-assembly of clathrin-inspired scaffolding nanoparticles. Colloids and Surfaces B: Biointerfaces, 2019, 176, 239. (SCI二区，selected as “Journal Cover”).
8. Yining Wu, Ruoyu Wang, Caili Dai*, Yan Xu, Tongtao Yue*, Mingwei Zhao*. Precisely Tailoring Bubble Morphology in Microchannel by Nanoparticles Self-assembly. Industrial & Engineering Chemistry Research, 2019, 58, 3707. (SCI二区, selected as “Journal Cover”).
9. Shixin Li, Zengshuai Yan, Zhen Luo, Yan Xu, Fang Huang, Guoqing Hu, Xianren Zhang, Tongtao Yue. Directional and Rotational Motions of Nanoparticles on Plasma Membranes as Local Probes of Surface Tension Propagation. Langmuir, 2019, 35, 5333. (SCI二区)
10. Haihong Huang, Baosheng Ge, Shuai Zhang, Jiqiang Li, Chenghao Sun, Tongtao Yue*, Fang Huang*. Using fluorescence quenching titration to determine the orientation of a model transmembrane protein in mimic membranes. Materials, 2019, 12, 349 (SCI三区).
11. Xiaofei Zhou, Jianbo Jia, Zhen Luo, Gaoxing Su, Tongtao Yue, Bing Yan*. Remote Induction of Cell Autophagy by 2D MoS2 Nanosheets via Perturbing Cell Surface Receptor and mTOR Pathway from Outside of Cell. ACS Applied Materials & Interfaces, 2019, 11, 6829. (SCI一区)
12. Hao Ren, Hongqin Chu, Zhongtao Li, Tongtao Yue, Zhenpeng Hu, Efficient energy gap tuning for T-carbon via single atomic doping. Chemical Physics, 2019, 518, 69. (SCI三区)

2018年：
13. Zhen Luo, Shixin Li, Yan Xu, Zengshuai Yan, Fang Huang, Tongtao Yue*. The role of nanoparticle shape in translocation across the pulmonary surfactant layer revealed by molecular dynamics simulations. Environmental Science: Nano, 2018, 5, 1921. (SCI一区)
14. Zhen Luo, Shixin Li, Yan Xu, Hao Ren, Xianren Zhang, Guoqing Hu, Fang Huang, Tongtao Yue*. Extracting pulmonary surfactants to form inverse micelles on suspended graphene nanosheets. Environmental Science: Nano, 2018, 5, 130. (SCI一区)
15. Zengshuai Yan, Shixin Li, Zhen Luo, Yan Xu, Tongtao Yue*. Membrane nanotube pearling restricted by confined polymers. Soft Matter, 2018, 14, 9383 (SCI二区).
16. Yan Xu, Shixin Li, Zengshuai Yan, Zhen Luo, Hao Ren, Baosheng Ge, Fang Huang, Tongtao Yue*. Stabilizing effect of inherent knots on proteins revealed by molecular dynamics simulations. Biophysical Journal, 2018, 115, 1681 (SCI二区).
17. Yan Xu, Shixin Li, Zhen Luo, Hao Ren, Xianren Zhang, Fang Huang, Yi Y. Zuo, Tongtao Yue*. The Role of Lipid Coating in Transport of Nanodroplets across the Pulmonary Surfactant Layer Revealed by Molecular Dynamics Simulations. Langmuir, 2018, 34, 9054. (SCI二区)
18. Falin Tian, Tongtao Yue, Wei Dong, Xin Yi, Xianren Zhang. Size-dependent formation of membrane nanotubes: continuum modeling and molecular dynamics simulations. Phys. Chem. Chem. Phys., 2018, 20, 3474. (SCI二区)
19. Jing Li, Xiuhua Liu, Falin Tian, Tongtao Yue, Xianren Zhang, Dapeng Cao. Spontaneous insertion of GPI anchors into cholesterol-rich membrane domains. AIP Advances, 2018, 8, 055210. (SCI三区)
20. Baoling Tian, Changhang Cheng, Tongtao Yue, Na Lin, Hao Ren. Chemical identification of the amyloid peptide aggregation-prone Al(III)-peptide complexes by resonance Raman signatures: A computational study. Chemical Physics, 2018, 513, 1-6. (SCI三区)

2017年：
21. Yan Xu, Zhen Luo, Shixin Li, Weiguo Li, Xianren Zhang, Yi Y. Zuo, Fang Huang, Tongtao Yue*. Perturbation of the pulmonary surfactant monolayer by single-walled carbon nanotubes: a molecular dynamics study. Nanoscale, 2017, 9, 10193. (SCI一区, selected as “Inside Back Cover”)
22. Yan Xu, Li Deng, Hao Ren, Xianren Zhang, Fang Huang, Tongtao Yue*. Transport of nanoparticles across pulmonary surfactant monolayer: a molecular dynamics study. Phys. Chem. Chem. Phys., 2017, 19, 17568. (SCI二区, selected as “2017 PCCP HOT ARTICLE”)
23. Shixin Li, Zhen Luo, Yan Xu, Hao Ren, Li Deng, Xianren Zhang, Fang Huang, Tongtao Yue*. Interaction pathways between soft lipid nanodiscs and plasma membranes: a molecular modeling study. BBA-Biomembranes, 2017, 1859, 2096. (SCI二区)
24. Tongtao Yue*, Yan Xu, Shixin Li, Zhen Luo, Xianren Zhang, Fang Huang. Ultrashort single-walled carbon nanotubes insert into a pulmonary surfactant monolayer via self-rotation: poration and mechanical inhibition. J. Phys. Chem. B, 2017, 121, 2797. (SCI三区)
25. Tongtao Yue*, Yan Xu, Shixin Li, Zhen Luo, Xianren Zhang, Fang Huang. Surface patterning of single-walled carbon nanotubes enhances their perturbation on a pulmonary surfactant monolayer: frustrated translocation and bilayer vesiculation. RSC Advances, 2017, 7, 20851. (SCI三区)
26. Xinli Gao, Tongtao Yue, Falin Tian, Zhiping Liu, Xianren Zhang. Erythrocyte membrane skeleton inhibits nanoparticle endocytosis. AIP Advances, 2017, 7, 065303. (SCI三区)
27. Xuejuan Liu, Falin Tian, Tongtao Yue, Xianren Zhang, Chongli Zhong. Pulling force and surface tension drive membrane fusion. J. Chem. Phys., 2017, 147, 194703. (SCI二区)
28. Hao Ren, Yu Zhang, Sibei Guo, Na Lin, Li Deng, Tongtao Yue, Fang Huang. Identifying the Cu(II)-Amyloid β peptide binding intermediates in the early stage of aggregation by resonance Raman spectroscopy: A simulation study. Phys. Chem. Chem. Phys., 2017, 19, 31103. (SCI二区)
2016年：
29. Tongtao Yue, Yan Xu, Shixin Li, Xianren Zhang, Fang Huang. Lipid extraction mediates aggregation of carbon nanospheres in pulmonary surfactant monolayers. Phys. Chem. Chem. Phys., 2016, 18, 18923. (SCI二区)
30. Tongtao Yue, Shixin Li, Yan Xu, Xianren Zhang, Fang Huang. Interplay between nanoparticle wrapping and clustering of inner anchored membrane proteins. J. Phys. Chem. B, 2016, 120, 11000. (SCI三区)
31. Tongtao Yue, Mingbin Sun, Shuai Zhang, Hao Ren, Baosheng Ge, Fang Huang. How transmembrane peptides insert and orientate in biomembranes: a combined experimental and simulation study. Phys. Chem. Chem. Phys., 2016, 18, 17483. (SCI二区)
32. Tongtao Yue, Falin Tian, Mingbin Sun, Xianren Zhang, Fang Huang. Inter-tube adhesion mediates a new pearling mechanism. Phys. Chem. Chem. Phys., 2016, 18, 361. (SCI二区)
33. Tongtao Yue, Yan Xu, Mingbin Sun, Xianren Zhang, Fang Huang. How tubular aggregates interact with biomembranes: wrapping, fusion and pearling. Phys. Chem. Chem. Phys., 2016, 18, 1082. (SCI二区)
34. Falin Tian, Tongtao Yue, Xianren Zhang, Wei Dong. Membrane tube pearling induced by a coupling of osmotic pressure and nanoparticle adhesion. Mol. Phys., 2016, 114, 2332. (SCI二区)
35. Xuejuan Liu, Falin Tian, Tongtao Yue, Xianren Zhang, Chongli Zhong. Exploring the shape deformation of biomembrane tubes with theoretical analysis and computer simulation. Soft Matter, 2016, 12, 9077. (SCI二区)
2015年：
36. Tongtao Yue, Xiaojuan Wang, Xianren Zhang, Fang Huang. Molecular modeling of interaction between lipid monolayer and graphene nanosheets: implications to pulmonary nanotoxicity and pulmonary drug delivery. RSC Advances, 2015, 9, 30092. (SCI二区)
37. Tongtao Yue, Xianren Zhang, Fang Huang. Molecular modeling of membrane responses to the adsorption of rotating nanoparticles: promoted cell uptake and mechanical membrane rupture. Soft Matter, 2015, 11, 456. (SCI二区)
2014年：
38. Tongtao Yue, Xianren Zhang, Fang Huang. The membrane monolayer protrusion mediates a new NP wrapping pathway. Soft Matter, 2014, 10, 2024. (SCI一区)
39. Tongtao Yue, Xianren Zhang, Fang Huang. Molecular modeling of membrane tube pearling and the effect of nanoparticle adsorption. Phys. Chem. Chem. Phys., 2014, 16, 10799. (SCI二区)
40. Falin Tian, Tongtao Yue, Ye Li, Xianren Zhang. Computer simulation studies on the interactions between nanoparticles and cell membrane. Sci. China Chem., 2014, 57, 1. (SCI三区)
41. Tongtao Yue, Diwen Feng, Xianren Zhang. The interplay between the clustering of transmembrane proteins and coupling of anchored membrane proteins. Molecular Simulation, 2014, 40, 922. (SCI四区)
2013年：
42. Tongtao Yue, Xiaojuan Wang, Fang Huang, Xianren Zhang. An Unusual Pathway for the Membrane Wrapping of Rodlike Nanoparticles and the Orientation- and Membrane Wrapping-dependent Nanoparticle Interaction. Nanoscale, 2013, 5, 9888. (SCI一区)
43. Tongtao Yue, Xianren Zhang. Molecular modeling of the pathways of vesicle–membrane interaction. Soft Matter, 2013, 9,559. (SCI一区)
2012年：
44. Tongtao Yue, Xianren Zhang. Cooperative effect in receptor-mediated endocytosis of multiple nanoparticles.ACS Nano, 2012, 6, 3196. (SCI一区)
45. Tongtao Yue, Xianren Zhang. Signal transduction across cellular membranes can be mediated by coupling of the clustering of anchored proteins in both leaflets.Phys. Rev. E, 2012, 85, 011917. (SCI二区)
46. Ye Li, Tongtao Yue, Kai Yang, Xianren Zhang. Molecular modeling of the relationship between nanoparticle shape anisotropy and endocytosis kinetics.Biomaterials, 2012, 33, 4965. (SCI一区)
2011年：
47. Tongtao Yue, Xianren Zhang. Molecular understanding of receptor-mediated membrane responses to ligand-coated nanoparticles.Soft Matter, 2011, 7, 9104. (SCI一区)
48. Tongtao Yue, Xianren Zhang. Self-assembly of semiflexible homopolymers into helical bundles: a brownian dynamics simulation study.J. Phys. Chem. B, 2011, 115, 11566. (SCI二区)
49. Tongtao Yue, Guangfeng Jiang, Xianren Zhang. Spontaneous pattern of linear molecules in strongly confined spaces.Phys. Chem. Chem. Phys., 2011, 13, 12497. (SCI二区)
2010年：
50. Tongtao Yue, Shuangyang Li, Xianren Zhang, Wenchuan Wang, The relationship between membrane curvature generation and clustering of anchored proteins: a computer simulation study. Soft Matter, 2010, 6, 6109. (SCI一区)
国际期刊Ecotoxicology and Environmental Safety（SCI二区，IF：4.527）的Expanded Editorial Board（扩大编委）；
中国化学会会员；
中国物理学会会员；
ACS Nano、Small、Nanoscale、Langmuir、Soft Matter、Scientific Reports等十余种SCI期刊审稿人。