个人简历

1982年 兰州大学化学系获学士学位\r
1985年 兰州大学化学系获硕士学位\r
1996年 日本千叶大学获博士学位\r
1985-1991年 华中师范大学化学系 教师\r
1991-1993年 日本茨城大学研修（日本文部省国费奖学金）\r
1996-1998年 武汉大学博士后\r
2000年 武汉大学化学系 教授\r
2000年6-9月 厦门大学化学系教育部高级访问学者\r
2002年8-11月美国Iowa州立大学和加州大学Riverside分校高级访问学者\r
2005年 获教育部新世纪优秀人才支持计划资助\r
2006年 获国家杰出青年科学基金资助\r
2009年 聘为武汉大学“珞珈”教授

研究领域

"""""（1）基于衍生化技术的复杂样品质谱分析新方法\r
（2）代谢组分析方法\r
（3）微型化样品前处理技术与色谱-质谱联用\r
（4）新型分离介质（整体柱、纳米材料、磁性材料等）"

近期论文

Xiao, H. M.; Yang, X.; Zheng, F.; Tshepelevitsh, S.; Wang, X.; Yao, X. J.; Leito, I.; Feng, Y. Q., Quantitative analysis of the relationship of derivatization reagents and detection sensitivity of electrospray ionization-triple quadrupole tandem mass spectrometry: Hydrazines as prototypes. Anal Chim Acta 2021, 1158, 338402.[DOI: 10.1016/j.aca.2021.338402]\r
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Cai, W. J.; Zeng, C.; Zhang, X. Y.; Ye, T.; Feng, Y. Q., A structure-guided screening strategy for the discovery and identification of potential gibberellins from plant samples using liquid chromatography-mass spectrometry assisted by chemical isotope labeling. Anal Chim Acta 2021, 1163, 338505.[DOI:10.1016/j.aca.2021.338505]\r
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Hu, Y.-N.; Zhan, J.-T.; Zhu, Q.-F.; Hu, T.; An, N.; Zhou, Z.; Liang, Y.; Wang, W.; Han, Z.; Wang, J.; Xu, F.-Q.; Feng, Y.-Q., A mathematical method for calibrating the signal drift in liquid chromatography - mass spectrometry analysis. Talanta 2021, 233.[DOI:10.1016/j.talanta.2021.122511]\r
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Wang, Q.; Ding, J.-H.; Xiong, J.; Feng, Y.; Yuan, B.-F.; Feng, Y.-Q., Site-specific quantification of 5-carboxylcytosine in DNA by chemical conversion coupled with ligation-based PCR. Chinese Chemical Letters 2021.[DOI: 10.1016/j.cclet.2021.05.020 ]\r
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Dai, Y.; Qi, C. B.; Feng, Y.; Cheng, Q. Y.; Liu, F. L.; Cheng, M. Y.; Yuan, B. F.; Feng, Y. Q., Sensitive and Simultaneous Determination of Uridine Thiolation and Hydroxylation Modifications in Eukaryotic RNA by Derivatization Coupled with Mass Spectrometry Analysis. Anal Chem 2021, 93 (18), 6938-6946.[DOI: 10.1021/acs.analchem.0c04630]\r
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Xiong, C. F.; Ding, J.; Zhu, Q. F.; Bai, Y. L.; Yin, X. M.; Ye, T. T.; Yu, Q. W.; Feng, Y. Q., Boron Isotope Tag-Assisted Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry for Discovery and Annotation of cis-Diol-Containing Metabolites. Anal Chem 2021, 93 (5), 3002-3009.[DOI:10.1021/acs.analchem.0c05037]\r
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Liu, F. L.; Ye, T. T.; Ding, J. H.; Yin, X. M.; Yang, X. K.; Huang, W. H.; Yuan, B. F.; Feng, Y. Q., Chemical Tagging Assisted Mass Spectrometry Analysis Enables Sensitive Determination of Phosphorylated Compounds in a Single Cell. Anal Chem 2021, 93 (17), 6848-6856.[DOI:10.1021/acs.analchem.1c00915 ]\r
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Chen, Y.-S.; Feng, Y.-Q., Rapid Determination of Endogenous 20-Hydroxyecdysone in Plants on MALDI-TOF/TOF Mass Spectrometry via Chemical Labeling Based on Boronate Affinity. Journal of Analysis and Testing2021.[DOI: 10.1007/s41664-021-00179-8]\r
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Dai, Y.; Yuan, B.-F.; Feng, Y.-Q., Quantification and Mapping of DNA Modifications. RSC Chemical Biology2021.[DOI:10.1039/D1CB00022E]\r
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Cheng, M.-Y.; You, X.-J.; Ding, J.-H.; Dai, Y.; Chen, M.-Y.; Yuan, B.-F.; Feng, Y.-Q., Novel dual methylation of cytidines in the RNA of mammals. Chemical Science 2021.[DOI:10.1039/d1sc01972d ]\r
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Zhao, Q.; Zhou, Y.-L.; Yue, S.-W.; Lou, Y.-J.; Feng, Y.-Q., Combination of Modified QuEChERS and Disposable Polyethylene Pipet Assisted DLLME Based on Low Density Solvent Extraction for Rapid and Sensitive Determination of Fipronil and Its Metabolites in Eggs by GC-MS. Food Analytical Methods2021, 14 (5), 1021-1032.[DOI:10.1007/s12161-020-01948-4]\r
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Xu, J.; Yuan, Y.; Chen, Y. Y.; Xiong, C. F.; Zhang, Z.; Feng, Y. Q., Carboxylic submetabolome-driven signature characterization of COVID-19 asymptomatic infection. Talanta2021, 239, 123086.[DOI:10.1016/j.talanta.2021.123086 ]\r
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Chen, M.-Y.; Gui, Z.; Chen, K.-K.; Ding, J.-H.; He, J.-G.; Xiong, J.; Li, J.-L.; Wang, J.; Yuan, B.-F.; Feng, Y.-Q., Adolescent alcohol exposure alters DNA and RNA modifications in peripheral blood by liquid chromatography-tandem mass spectrometry analysis. Chinese Chemical Letters 2021.[DOI:10.1016/j.cclet.2021.08.094]\r
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Chen, M.-Y.; Qi, C.-B.; Tang, X.-M.; Ding, J.-H.; Yuan, B.-F.; Feng, Y.-Q., Comprehensive profiling and evaluation of the alteration of RNA modifications in thyroid carcinoma by liquid chromatography-tandem mass spectrometry. Chinese Chemical Letters2021.[DOI: 10.1016/j.cclet.2021.12.008]\r
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Wang, R. Q.; Ding, J.; Geng, Y.; Li, Y. Z.; Mei, Y. W.; Bao, K.; Yu, H. D.; Feng, Y. Q., CRB-SWATH: A Method for Enhancing Untargeted Precursor Ion Extraction and Automatically Constructing Their Tandem Mass Spectra from SWATH Datasets by Chromatographic Retention Behaviors. Anal Chem 2021, 93 (36), 12273-12280.[DOI:10.1021/acs.analchem.1c01841]\r
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Xiong, C. F.; Zhu, Q. F.; Chen, Y. Y.; He, D. X.; Feng, Y. Q., Screening and Identification of Epoxy/Dihydroxy-Oxylipins by Chemical Labeling-Assisted Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry. Anal Chem2021, 93 (28), 9904-9911.[DOI:10.1021/acs.analchem.1c02058]\r
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An, N.; Zhu, Q. F.; Wang, Y. Z.; Xiong, C. F.; Hu, Y. N.; Feng, Y. Q., Integration of Chemical Derivatization and in-Source Fragmentation Mass Spectrometry for High-Coverage Profiling of Submetabolomes. Anal Chem 2021, 93 (32), 11321-11328.[DOI:10.1021/acs.analchem.1c02673]\r
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Feng, Y.; Chen, J. J.; Xie, N. B.; Ding, J. H.; You, X. J.; Tao, W. B.; Zhang, X.; Yi, C.; Zhou, X.; Yuan, B. F.; Feng, Y. Q., Direct decarboxylation of ten-eleven translocation-produced 5-carboxylcytosine in mammalian genomes forms a new mechanism for active DNA demethylation. Chem Sci 2021, 12 (34), 11322-11329.[DOI:10.1039/d1sc02161c]\r
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Ma, C. J.; Li, L.; Shao, W. X.; Ding, J. H.; Cai, X. L.; Lun, Z. R.; Yuan, B. F.; Feng, Y. Q., An enzyme-mediated bioorthogonal labeling method for genome-wide mapping of 5-hydroxymethyluracil. Chem Sci 2021, 12 (42), 14126-14132.[DOI:10.1039/d1sc03812e]\r
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Yin, X.; Bai, Y. L.; Ye, T.; Yu, M.; Wu, Y.; Feng, Y. Q., Cinnamoyl coA:NADP oxidoreductase like 1 regulates abscisic acid response by modulating phaseic acid homeostasis in Arabidopsis thaliana. Journal of experimental botany2021.[DOI:10.1093/jxb/erab474]