个人简历

教育背景 博士(2005-2007): Chemical/Biochemical Engineering, University of Waterloo, Canada 硕士(1985-1988): 大连理工大学, 化学工程（生物化工）专业 学士(1981-1985): 大连理工大学, 化工机械专业 工作经历 2013.01至今: 上海交通大学生物科学技术学院特聘教授 1999. 08-2012. 12: 大连理工大学生物科学技术学院教授 1995. 07-1999. 07: 大连理工大学化工学院副教授 1990. 07-1995. 06: 大连理工大学化工学院讲师 1988. 06-1990. 06: 大连理工大学化工学院助教 其中： 1999.09-2000.02: Visiting Scholar, Ohio University, USA 2002.11-2003.06: Visiting Scholar, University of Waterloo, Canada 2010.03-2010.12: Visiting Professor, Massachusetts Institute of Technology, USA

研究领域

长期从事工业生物技术基础研究和创新技术开发，以生物能源产品生产为主要研究方向。系统提出了利用现代生物技术改造或选育目标产物合成性能优良且具有自絮凝能力的菌株，以细胞自絮凝形成颗粒作为细胞固定化方法的自固定化细胞技术的概念，研究开发了工程放大技术。以乙醇发酵为模式体系，采用原生质体融合技术选育发酵性能优良且具有自絮凝能力的酵母菌株，开发了自固定化酵母细胞乙醇连续发酵新技术，并在国家燃料乙醇试点工程建设中得到应用。与现有乙醇发酵技术相比，平均发酵时间显著缩短，发酵罐设备生产强度相应提高；由于酵母细胞以自絮凝颗粒的形态在发酵罐中实现固定化，乙醇精馏后产生废糟液的COD大幅度降低，为燃料乙醇生产源头减废，清洁生产创造了有利条件。

近期论文

Liu CG, Xue C, Bai FW, Lin YH. Redox potential control and applications in micro-aerobic and anaerobic fermentations. Biotechnology Advances, in press Liu Z, Zhao XQ, Bai FW. Identification of an alkaline tolerant marine-derived Streptomyces strain as a xylanase producer and improvement of its xylanase production by ribosome engineering. Applied Microbiology and Biotechnology, in press. Xue C, Zhao JB, Liu FF, Lu CC, Yang ST, Bai FW. Two-stage in situ gas stripping for enhanced butanol fermentation and energy-saving product recovery. Bioresource Technology, in press. Chun W, Zhao XQ, Guo SL, Alam MA, Bai FW. Efficient cell harvest of marine microalga Nannochloropsis oceanica using bioflocculant produced by Solibacillus silvestris and optimization of bioflocculant production. Bioresource Technology, in press. Guo SL, Zhao XQ, Tang Y, Alam MA, Wan C, Ho SH, Bai FW, Chang JS. 2013. Establishment of an efficient genetic transformation system in Scenedesmus obliquus. Journal of Biotechnology 163: 61-68. Zhao N, Bai Y, Zhao XQ, Bai FW. 2012. Draft genome sequence of the flocculating Zymomonas mobilis strain ZM401. Journal of Bacteriology 194: 7008-9. Liu CG, Wang N, Lin YH, Bai FW. 2012. Very-high-gravity ethanol fermentation by flocculating yeast under redox potential-controlled conditions. Biotechnology for Biofuels 5: 61. Xue C, Zhao JB, Lu CC, Yang ST, Bai FW, Tang IC. 2012. High-titer n-butanol production by Clostridium acetobutylicum JB200 in fed-batch fermentation with intermittent gas stripping. Biotechnology and Bioengineering 109: 2746-56. He LY, Zhao XQ, Bai FW. 2012. Engineering industrial Saccharomyces cerevisiae strain with the FLO1-derivative gene isolated from the flocculating yeast SPSC01 for constitutive flocculation and fuel ethanol production. Applied Energy 100: 33-40. Zhao XQ, Li Q, He LY, Li F, Que WW, Bai FW. 2012. Exploration of a natural reservoir of flocculating genes from various Saccharomyces cerevisiae strains and improved ethanol fermentation using stable genetically engineered flocculating yeast strains. Process Biochemistry 47: 1612-19. He LY, Zhao XQ, Ge XM. Bai FW. 2012. Identification and functional study of a new FLO10-derivative gene from the industrial flocculating yeast SPSC01. Journal of Industrial Microbiology and Biotechnology 39: 1135-40. Xie HB, Shen HW, Gong ZW, Wang Q, Zhao ZK, Bai FW. 2012. Enzymatic hydrolysates of corn stover pretreated by a N-methylpyrrolidone-ionic liquid solution for microbial lipid production. Green Chemistry 14: 1202-10. Zhao XQ, Bai FW. 2012. Zinc and yeast stress tolerance. Journal of Biotechnology 158: 176-83. Li Q, Zhao XQ, Chang AK, Zhang QM, Bai FW. 2012. Ethanol-induced yeast flocculation directed by the promoter of TPS1 encoding trehalose-6-phosphate synthase 1 for efficient ethanol production. Metabolic Engineering 14: 1-8. Yuan WJ, Chang BL, Ren JG, Bai FW, Li YY. 2012. Consolidated bioprocessing strategy for ethanol production from Jerusalem artichoke tubers by K. marxianus under high gravity conditions. Journal of Applied Microbiology 112: 38-44. Liu CG, Lin YH, Bai FW. 2012. Ageing vessel design and optimization for continuous very-high-gravity ethanol fermentation processes. Process Biochemistry 47: 57-61. Liu CG, Lin YH, Bai FW. 2011. A kinetic growth model for Saccharomyces cerevisiae grown under redox potential-controlled very-high-gravity environment. Biochemical Engineering Journal 56: 63-68. Liu CG, Lin YH, Bai FW. 2011. Development of continuous redox potential-controlled fermentation process for ethanol production. Journal of Biotechnology 153: 42-47. Liu CG, Lin YH, Bai FW. 2011. Ageing vessel configuration for continuous redox potential-controlled very-high-gravity fermentation. Journal of Bioscience and Bioengineering 111: 61-66. Yu L, Wang H, Wang L, Bai FW. 2010. Rheological property of self-flocculating yeast suspension. Biochemical Engineering Journal 52: 50-54.