个人简历

2000-2004 哈尔滨理工大学 化学环境与工程学院 学士
2005-2010 国家纳米科学中心 物理化学 博士
2010-2013 丹麦奥胡斯大学 多学科交叉纳米中心（iNANO Center） 博士后
2014-至今 江苏大学 新材料研究院 江苏特聘教授，研究员，青年特聘教授

研究领域

扫描探针显微镜研究，
生物分子自组装纳米材料构建与应用，
生物分子自组装与疾病致病机理研究，
二维无机材料与生物分子相互作用研究

近期论文

1. Lei Liu, Lan Zhang, Xiaobo Mao, Lin Niu, Yanlian Yang*, Chen Wang*. Chaperon-mediated single molecular approach towards modulating Aβ peptide aggregation. Nano Lett., 9, 4066-4072., 2009.
2. Lei Liu, Lang Zhang, Lin Niu，Meng Xu, XiaoBo Mao, Yanlian Yang* and Chen Wang*. Observation of Reduced Cytotoxicity of Aggregated Amyloidogenic Peptides with Chaperone-like Molecules. ACS NANO, 5, 6001-6007., 2011.
3. Lei Liu, Lin Niu, Meng Xu, Qiusen Han, Hongyang Duan, Mingdong Dong, Flemming Besenbacher,Chen Wang,* and Yanlian Yang*. Molecular tethering effect of C-terminus of amyloid peptide Aβ42. ACS NANO, 8, 9503-9510., 2014.
4. Lin Niu, Lei Liu(equal contribution), Meng Xu, Jacob Cramer,Kurt V. Gotherlf, Mingdong Dong, Flemming Besenbacher, Qingdao Zeng, Yanlian Yang, Chen Wang. Transformation of beta sheet structure of amyloid peptide induced by molecular modulators. Chem. Commun.50, 8923-8926,2014.
5. Lei Liu, Katerina Busuttil, Shuai Zhang, Yanliang Yang, Chen Wang, Flemming Besenbacher and Mingdong Dong*. The role of self-assembling polypeptide in building nanomaterials. Phys. Chem. Chem. Phys., 13, 17435-17444., 2011.
6. Ma, X. J.; Lei, Liu. (Equal contribution); Mao, X. B.; Niu, L.; Deng, K.; Wu, W. H.; Li, Y. M.; Yang, Y. L.; Wang, C*. Amyloid-β (1-42) folding multiplicity and single molecule binding behavior studied by STM. J. Mol. Biol. 388, 894-901., 2009.
7. Guanghong Zeng, Lei Liu (Equal contribution), Dan Xia, Qiang Li, Zhuo Xin, JianGuo Wang, Flemming Besenbacher, Troels Skrydstrup and Mingdong Dong*. Transition of Chemical modified diphenylalanine peptide assemblies revealed by atomic force microscopy. RSC Adv., 4, 7516-7520., 2014.
8. Qiang Li, Lei Liu (Equal contribution)，Shuai Zhang, Meng Xu, Xueqing Wang, Chen Wang, Flemming Besenbacher, Mingdong Dong*. Modulating Aβ33-42 peptide assembly by graphene oxide. Chem. Eur.J. 20, 7236-7240, 2014.
9. Lei Liu, Yibao Li, Dan Xia, Christian Bortolini, Shuai Zhang, Yanlian Yang, Jan. S.Pedersen, Chen Wang, Flemming Besenbacher, Mingdong Dong*. Self-assembled nanopatch with peptide-organic multilayers and mechanical property. Nanoscale. DOI: 10.1039/c4nr03797a， 2014.
10. YinLi Li，Lei Liu, (Equal contribution), Ramesh Subramani, Yunxiang Pan, Bo Liu, Yanlian Yang, Chen Wang, Wael Mamdouh, Flemming Besenbacher and Mingdong Dong*. Building layer-by-layer 3D supramolecular nanostructures at the terephthalic acid/stearic acid interface. Chem. Commun., 47, 9155-9157.,2011.
11. Lin Lin, Haiying Cui, Hui Zhou, Xuejing Zhang, Christian Bortolini, Menglin Chen, Lei Liu* and Mingdong Dong*. Nanoliposomes containing Eucalyptus citriodora as antibiotic with specific antimicrobial activity. Chem. Commun. DOI: 10.1039/c4cc09386k. 2014.
12. Lei Liu.; Yang Y L; Wang C*.; Yao Y.; Ma Y Z.; Hou S. ; Feng X Z*. Polymeric effects in DNA condensation by cationic polymers observed by atomic force microscopy. Colloids and Surface B: Biointerface. 75, 230-238., 2010.
13. Christian Bortolini, Lei Liu, Thomas M.A. Gronewold, Chen Wang, Flemming Besenbacher and Mingdong Dong*.The position of hydrophobic residues tunes peptide self-assembly. Soft Matt. 10， 5656-5661， 2014
14. Christian Bortolini, Lei Liu, Zhenshen Li, Karen Thomsen, Chen Wang, Flemming Besenbacher* and Mingdong Dong*. Identification of cysteine-rich peptide fiber by specific cysteine-Au nanoparticles binding on fiber surface. Adv. Mater. Interfaces. DOI: 10.1002/admi.201400133. 2014.
15. Shuai Zhang, Maria Andreasen, Jakob T. Nielsen, Lei Liu, Erik H. Nielsen, Daniel E. Otzen, Mingdong, Dong*. Coexistence of ribbon and helical fibrils originating from hIAPP20-29 revealed by quantitative nanomechanical atomic force microscopy. Proc. Natl. Acad. Sci., U S A ，110, 2798-803., 2013.
16. Shuang Song, Ling-Zhi Cheong, Mia Falkeborg, Lei Liu, Mingdong Dong, Henrik Max Jensen, Kresten Bertelsen, Michael Thorsen, Tianwei Tan*, Xuebing Xu, Zheng Guo*. Facile Synthesis of Phosphatidyl Saccharides for Preparation of Anionic Nanoliposomes with Enhanced Stability. Plos One， 8，1-11.， 2013.
17. Xiao-Bo Mao, Chen-Xuan Wang, Xing-Kui Wu, Xiao-Jing Ma, Lei Liu, Lan Zhang, Lin Niu, Yuan-Yuan Guo, Deng-Hua Li, Yan-Lian Yang, and Chen Wang*. Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies. Proc. Natl. Acad. Sci., U S A, 108, 19605-19610., 2011.
18. Jie Song, Jean-Michel Arbona, Zhao Zhang, Lei Liu, Erqing Xie, Juan Elezgaray, Jean-Pierre Aimé, Kurt V. Gothelf, Flemming Besenbacher, and Mingdong Dong*. Direct Visualization of Transient Thermal Response of a DNA Origami. J. Am. Chem. Soc., 134, 9844–9847., 2012.
19. Xiaobo Mao, Yuanyuan Guo, Yin Luo, Lin Niu, Lei Liu, Xiaojing Ma, Huibin Wang, Yanlian, Yang, Guanghong Wei and Chen Wang*. Sequence effects on peptide assembly characteristics observed by using scanning tunneling microscopy. J. Am. Chem. Soc., 135, 2181–2187., 2013.
20. Jie Song, Zhao,Zhang, Shuai Zhang, Lei Liu, Qiang Li, Erqing, Xie, Kurt. V. Gothelf, Flemming Besenbacher, Mingdong Dong*. Isothermal hybridization kinetics of DNA assembly of two dimensional DNA origami. Small, 9, 2954-2959., 2013.