个人简历

教育背景\r
2005-2009 南京大学化学系 化学学士\r
2009-2015 美国伊利诺伊大学（香槟校区）化学系 化学博士\r
2015-2017 美国伊利诺伊大学（香槟校区）化学系 博士后研究员\r
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工作履历\r
2017至今 湖南大学化学生物学与纳米医学研究所 化学生物传感与计量学国家重点实验室 湖南大学化学化工学院 教授

研究领域

""1. 以有机化学、高分子化学为基础的生物兼容有机纳米粒子的合成与应用\r
2. 可在细胞内进行催化反应的金属有机催化剂的研究与合成\r
3. 新型多途径高分子抗菌化合物的合成与机理研究""""

近期论文

Yingjiao Deng, Tong Wu*, Xianhui Chen, Yuanyuan Chen, Yating Fei, Ying Liu, Zhiyong Chen, Hang Xing and Yugang Bai*, A Membrane Embedded Macromolecular Catalyst with Substrate Selectivity in Live Cells. J. Am. Chem. Soc. 2022, ASAP. \r
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Zehong Cheng, Jing Guo, Jia Pan, Ying Liu, Huan Wei, Jishan Li, Song Liu,* Yuanyuan Hu,* and Yugang Bai*, Accelerated Preparation of Polypeptides and Related Hybrid Materials from A Disintegrable Initiator Array with Masked Carbenium Precursors. Chem. Mater. 2022, 34, 10732-10743.\r
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Zehong Cheng, Guokui Zheng, Ziqi Tian,* Xiangyu Chao, Yue Xiao, Jishan Li, and Yugang Bai*, Multivalency for Modularity: A Versatile Adhesive with Cooperatively Activated Fast Dismantlability. ACS Appl. Polym. Mater. 2022, 4, 6812-6816.\r
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Jing Guo, Ying Liu, Ping-An Chen, Xinhao Wang, Yanpei Wang, Jing Guo, Xincan Qiu, Zebing Zeng, Lang Jiang, Yuanping Yi, Shun Watanabe, Lei Liao, Yugang Bai*, Thuc-Quyen Nguyen*, Yuanyuan Hu*, Revealing the Electrophilic-Attack Doping Mechanism for Efficient and Universal p-doping of Organic Semiconductors. Adv. Sci. 2022, 9, 2203111.\r
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Xianhui Chen, Cailing Zhou, Jianxue Wang, Tong Wu, E Lei, Yi Wang, Guopu Huang, Yue Yu, Qingyun Cai,* Huangsheng Pu,* Xinxin Feng,* and Yugang Bai,* Improving the Hemocompatibility of Antimicrobial Peptidomimetics through Amphiphilicity Masking Using a Secondary Amphiphilic Polymer. Adv. Healthcare Mater. 2022, 11, 2200546.\r
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Guopu Huang, Hui Shen, Xianhui Chen, Tong Wu, Zhiyong Chen, Yajie Chen, Junfeng Song, Qingyun Cai,* Yugang Bai,* Huangsheng Pu* and Xinxin Feng*, A Degradable, Broad-Spectrum and Resistance-Resistant Antimicrobial Oligoguanidine as Disinfecting and Therapeutic Agent in Aquaculture. Polym. Chem. 2022, 13, 3539-3551. \r
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Zhiyong Chen, Wanqi Zhang, Yajie Chen, Yingjie Wang,* Silei Bai, Qingyun Cai, Huangsheng Pu,* Zuyong Wang,* Xinxin Feng* and Yugang Bai,* Alternatingly Amphiphilic Antimicrobial Oligoguanidines: Structure-Property Relationship and Usage as Coating Material with Unprecedented Hemocompatibility. Chem. Mater. 2022, 34, 3670–3682. \r
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Jianxue Wang, Junfeng Song, Xianhui Chen, Rey-Ting Guo, Yingjie Wang, Guopu Huang, Nan Zheng, Peilei Hu*, Xinxin Feng* and Yugang Bai,* Multivalent Display of Lipophilic DNA Binders for Dual-Selective Anti-Mycobacterium Peptidomimetics with Binary Mechanism of Action. CCS Chem. 2022, 4, 3573-3586.\r
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Bohan Zhang, Silei Bai, Xiangyu Chao, Tong Wu, Zhiyong Chen, Zehong Cheng, Yue Xiao, Ke Zhang* and Yugang Bai,* Molecularly Pure Miktoarm Spherical Nucleic Acids: Preparation and Usage as Scaffold for Abiotic Intracellular Catalysis. Chem. Sci. 2021, 12, 15843-15848.\r
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Yanhong Liu, Silei Bai, Tong Wu, Chun-Chi Chen, Ying Liu, Xiangyu Chao, Yugang Bai,* Dendronized Arm Snowflake Polymer as a Highly Branched Scaffold for Cellular Imaging and Delivery. Biomacromolecules 2021, 22, 3791–3799.\r
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Zhiyong Chen, Cailing Zhou, Yangfan Xu, Kang Wen, Junfeng Song, Silei Bai, Chenxuan Wu, Wei Huang, Qingyun Cai, Kai Zhou, Hui Wang, Yingjie Wang,* Xinxin Feng,* Yugang Bai*, An Alternatingly Amphiphilic, Resistance-Resistant Antimicrobial Oligoguanidine with Dual Mechanisms of Action. Biomaterials 2021, 275, 120858.\r
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Silei Bai, Jianxue Wang, Kailing Yang, Cailing Zhou, Yangfan Xu, Junfeng Song, Yuanxin Gu, Zheng Chen, Min Wang, Carolyn Shoen, Brenda Andrade, Michael Cynamon, Kai Zhou, Hui Wang, Qingyun Cai, Eric Oldfield, Steven C. Zimmerman, Yugang Bai,* and Xinxin Feng,* A Polymeric Approach toward Resistance-Resistant Antimicrobial Agent with Dual-Selective Mechanisms of Action. Sci. Adv. 2021, 7, eabc9917.\r
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Ying Liu, Yugang Bai,* Design and Engineering of Metal Catalysts for Bioorthogonal Catalysis in Living Systems. ACS Appl. Bio Mater. 2020, 3, 4717. [Link]\r
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Yugang Bai, Hang Xing, Yunhao Bai, Li Huey Tan, Kevin Hwang, Ji Li, Yi Lu*, and Steven C. Zimmerman,* Independent Control over Size, Valence, and Elemental Composition in the Synthesis of DNA-Nanoparticle Conjugates. Chem. Sci. 2020, 11, 1564.\r
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Qing Lu, Silei Bai, Zhiyong Chen, Nan Zheng, Xinxin Feng, Yugang Bai*, A Dense-Shell Macromolecular Scaffold for Catalyst- or Substrate-Guided Catalysis in a Cellular Environment. ACS Materials Lett. 2020, 2, 89. \r
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Zhiyong Chen, Wei Huang, Nan Zheng*, Yugang Bai*, Design and Synthesis of a Polyguanidium Vector with Enhanced DNA Binding Ability for Effective Gene Delivery at a Low N/P Ratio. Polym. Chem. 2020, 11, 664. \r
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Nan Zheng, Dan Xie, Chunsen Wang, Zhiyi Zhang, Yubin Zheng, Qing Lu, Yugang Bai, Yang Li, Aiguo Wang*, Wangze Song*, Water-Soluble, Zwitterionic Poly-Photosensitizers as Carrier-Free, Photosensitizer-Self-Delivery System for in Vivo Photodynamic Therapy. ACS Appl. Mater. Interfaces 2019, 11, 44007. \r
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Nan Zheng, Zhiyi Zhang, Jia Kuang, Chunsen Wang, Yubin Zheng, Qing Lu, Yugang Bai, Yang Li, Aiguo Wang, Wangze Song*, Poly (photosensitizers) Nanoparticles for Enhanced In Vivo Photodynamic Therapy by Interrupting the π-π Stacking and Extending Circulation Time. ACS Appl. Mater. Interfaces 2019, 11, 18224. \r
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JuYeon Lee, Yugang Bai, Ullas V. Chembazhi, Shaohong Peng, Kevin Yum, Long M. Luu, Lauren D. Hagler, Julio F. Serrano, H. Y. Edwin Chan, Auinash Kalsotra*, and Steven C. Zimmerman*, Intrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1. Proc. Natl. Acad. Sci. U. S. A. 2019, 116, 8709. \r
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Yue Xiao, Yang Li, Bohan Zhang, Hui Li, Zehong Cheng, Jianqiao Shi, Jing Xiong, Yugang Bai, and Ke Zhang*, Functionalizable, Side Chain-Immolative Poly(benzyl ether)s. ACS Macro Lett. 2019, 8, 399.