个人简历

1979年9月生，辽宁省铁岭市人。生物材料与组织工程专业博士，生物医学工程专业博士后，中国生物材料学会会员，江苏省先进金属材料高技术研究重点实验室秘书。教育经历: 2005.3～2010.6东南大学材料科学与工程学院，生物材料与组织工程专业，工学博士，导师：林萍华教授，董寅生教 2002.9～2005.3东南大学材料科学与工程学院，材料加工工程专业，工学硕士，导师：林萍华教授，董寅生教授 1998.9～2002.6东南大学机械工程系，材料成型及控制工程专业（主修）/工业管理工程专业（辅修），工学学士，指导老师：高锦张副教授，戴挺副教授 工作经历: 2016.12至今，东南大学材料学科与工程学院，讲师 2014.5～2016.12，密西根大学化学系/东南大学生物科学与医学工程学院，博士后，合作导师：Prof. Zhan Chen，顾宁教授 2010.7～2014.5，东南大学生物科学与医学工程学院，生物医学工程专业，博士后，合作导师：顾宁教授

研究领域

1. 功能纳米材料合成及其生物医学应用 2. 生物材料与组织工程 3. 仿生材料、生物矿化 4. 材料的表界面研究 5. 材料加工制备技术

近期论文

1. Jun Lin, Yiming Liu, Hao Wu, Zhihai Huang, Jingfan Ma, Chang Guo, Feng Gao, Peipei Jin, Pengfei Wei, Yunjiao Zhang, Liu Liu, Rui Zhang, Longxin Qiu, Ning Gu, Longping Wen. Key Role of TFEB Nucleus Translocation for Silver Nanoparticle-Induced Cytoprotective Autophagy[J]. Small, 2018, 13(14): 1703711(1-10) 2. Lingying Zhu, Dawei Guo (co-first author), Lili Sun, Zhihai Huang, Xiuyan Zhang, Wenjuan Ma, Jie Wu, Lu Xiao, Yun Zhao, Ning Gu. Activation of autophagy by elevated reactive oxygen species rather than released silver ions promotes cytotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in hematopoietic cells[J]. Nanoscale, 2017, 9(17): 5489-5498 3. Qi Ding, Dongfang Liu, Dawei Guo, Fang Yang, Xingyun Pang, Renchao Che, Naizhen Zhou, Jun Xie, Jianfei Sun, Zhihai Huang, Ning Gu. Shape-controlled fabrication of magnetite silver hybrid nanoparticles with high performance magnetic hyperthermia[J]. Biomaterials, 2017, 124: 35-46 4. Hao Wu, Jun Lin, Peidang Liu, Zhihai Huang, Peng Zhao, Haizhen Jin, Jun Ma, Longping Wen, Ning Gu. Reactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPs[J]. Biomaterials, 2016, 101: 1-9 5. Zhihai Huang, Hao Jiang, Peidang Liu, Jianfei Sun, Dawei Guo, Jieling Shan, Ning Gu. Continuous synthesis of size-tunable silver nanoparticles by green electrolysis method and multi-electrode design for high yield[J]. Journal of Materials Chemistry A, 2015, 3: 1925-1929 6. Hao Wu, Jun Lin, Peidang Liu, Zhihai Huang, Peng Zhao, Haizhen Jin, Cailian Wang, Longping Wen, Ning Gu. Is the autophagy a friend or foe in the silver nanoparticles associated radiotherapy for glioma?[J]. Biomaterials, 2015, 62: 47-57 7. Dawei Guo, Dandan Dou, Lin Ge, Zhihai Huang, Liping Wang, Ning Gu. A caffeic acid mediated facile synthesis of silver nanoparticles with powerful anti-cancer activity[J]. Colloids and Surfaces B: Biointerfaces, 2015, 134: 229-234 8. Dawei Guo, Junren Zhang,Zhihai Huang, Shanxiang Jiang, Ning Gu. Colloidal silver nanoparticles improves anti-leukemic drug efficacy via amplification of oxidative stress[J]. Colloids and Surfaces B: Biointerfaces, 2015, 126: 198-203 9. Jun Lin, Zhihai Huang, Hao Wu, Wei Zhou, Peipei Jin, Pengfei Wei, Yunjiao Zhang, Fang Zheng, Jiqian Zhang, Jing Xu, Yi Hu, Yanhong Wang, Yajuan Li, Ning Gu, Longping Wen. Inhibition of autophagy enhances the anticancer activity of silver nanoparticles[J]. Autophagy, 2014, 10(11): 2006-2020 10. Dawei Guo, Yun Zhao, Yu Zhang, Qing Wang, Zhihai Huang, Qi Ding, Zhirui Guo, Xuefeng Zhou, Lingying Zhu, Ning Gu, The Cellular Uptake and Cytotoxic Effect of silver Nanoparticles on Chronic Myeloid Leukemia Cells[J]. Journal of Biomedical Nanotechnology, 2014, 10(4): 669-678 11. Peidang Liu, Zhihai Huang (co-first author), Zhongwen Chen, Ruizhi Xu, Hao Wu, Fengchao Zang, Cailian Wang, Ning Gu. Silver nanoparticles: a novel radiation sensitizer for glioma?[J]. Nanoscale, 2013, 5: 11829-11836 12. Zhihai Huang, Qing Wang, Zhirui Guo, Lina Xu, Dongfang Liu, Qi Ding, Ning Gu. Rapid synthesis of high-stable silver nanoparticles by electrochemical method[J]. Nanoscience and Nanotechnology Letters, 2013, 5(2): 232-236 13. Dawei Guo, Lingying Zhu, Zhihai Huang, Haixia Zhou, Yue Ge, Wenjuan Ma, Jie Wu, Xiuyan Zhang, Xuefeng Zhou, Yu Zhang, Yun Zhao, Ning Gu. Anti-leukemia activity of PVP-coated silver nanoparticles via generation of reactive oxygen species and release of silver ions[J]. Biomaterials, 2013, 34(32): 7884-7894 14. Peidang Liu, Zhihai Huang, Ning Gu. Exposure to silver nanoparticles does not affect cognitive outcome or hippocampal neurogenesis in adult mice[J]. Ecotoxicology and Environmental Safety, 2013, 87: 124-130 15. Jun Dou, Xiangfeng He (co-first author), Yunjing Liu (co-first author), Zhihai Huang, Cuiping Yang, Fangfang Shi, Dengyu Chen, Ning Gu. Targeted therapeutic effect of anti-ABCG2 antibody combined with nano silver and vincristine on mouse myeloma cancer stem cells[J]. Journal of Nanoparticle Research, 2013, 15: 2127-2141 16. Dawei Guo, Xiuyan Zhang (co-first author), Zhihai Huang, Xuefeng Zhou, Lingying Zhu, Yun Zhao, Ning Gu. Comparison of cellular responses across multiple passage numbers in Ba/F3-BCR-ABL cells induced by silver nanoparticles[J]. Science China (Life Sciences), 2012, 55(10), 898-905 17. Zhihai Huang, Xiaoli Jiang, Dawei Guo, Ning Gu. Controllable synthesis and biomedical applications of silver nanomaterials[J]. Journal of Nanoscience and Nanotechnology, 2011, 11: 9395-9408 18. Zhihai Huang, Yinsheng Dong, Pinghua Lin. Depositing an Apatite Coating in/on Massive Chitosan Porous Scaffolds by an Alternate Soaking Method[J]. Acta Physico-Chimica Sinica, 2009, 25(7): 1285-1289 (in Chinese)