个人简历

研究领域

With a focus on growth factor receptor signalling, the aim of our research is the discovery of novel biological principles and mechanisms of general importance for nervous system development and metabolic""

近期论文

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1. Yi, C., Goh, K. Y., Wong, L. W., Ramanujan, A., Tanaka, K., Sajikumar, S., & Ibanez, C. F. (2021).Inactive variants of death receptor p75(NTR) reduce Alzheimer's neuropathology by interfering with APP internalization. EMBO J, 40(2), e104450. doi:10.15252/embj.2020104450\r
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2. Gongrich, C., Krapacher, F. A., Munguba, H., Fernandez-Suarez, D., Andersson, A., Hjerling-Leffler, J., & Ibanez, C. F. (2020). ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons. J Cell Biol, 219(1). doi:10.1083/jcb.201905002\r
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3. Marmol, P., Krapacher, F., & Ibanez, C. F. (2020). Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7. Elife, 9. doi:10.7554/eLife.54721\r
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4. Guo, T., Marmol, P., Moliner, A., Bjornholm, M., Zhang, C., Shokat, K. M., & Ibanez, C. F. (2014). Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity. Elife, 3, e03245. doi:10.7554/eLife.03245\r
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5. Vilar, M., Charalampopoulos, I., Kenchappa, R. S., Simi, A., Karaca, E., Reversi, A., . . . Ibanez, C. F. (2009). Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers. Neuron, 62(1), 72-83. doi:10.1016/j.neuron.2009.02.020\r
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6. Bertolino, P., Holmberg, R., Reissmann, E., Andersson, O., Berggren, P. O., & Ibanez, C. F. (2008). Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function. Proc Natl Acad Sci U S A, 105(20), 7246-7251. doi:10.1073/pnas.0801285105\r
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7. Ledda, F., Paratcha, G., Sandoval-Guzman, T., & Ibanez, C. F. (2007). GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion. Nat Neurosci, 10(3), 293-300. doi:10.1038/nn1855\r
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8. Vilar, M., Murillo-Carretero, M., Mira, H., Magnusson, K., Besset, V., & Ibanez, C. F. (2006). Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle. EMBO J, 25(6), 1219-1230. doi:10.1038/sj.emboj.7601017\r
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9. Pozas, E., & Ibanez, C. F. (2005). GDNF and GFRalpha1 promote differentiation and tangential migration of cortical GABAergic neurons. Neuron, 45(5), 701-713. doi:10.1016/j.neuron.2005.01.043\r
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10. Paratcha, G., Ledda, F., & Ibanez, C. F. (2003). The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands. Cell, 113(7), 867-879. doi:10.1016/s0092- 8674(03)00435-5\r
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11. Ledda, F., Paratcha, G., & Ibanez, C. F. (2002). Target-derived GFRalpha1 as an attractive guidance signal for developing sensory and sympathetic axons via activation of Cdk5. Neuron, 36(3), 387- 401. doi:10.1016/s0896-6273(02)01002-4