个人简介
EducationPh.D. Molecular Biology and Biochemistry,Rutgers University, USAM.S. Plant Genetics and Breeding,Beijing Agricultural University, ChinaB.S. Plant Genetics and Breeding,Beijing Agricultural University, ChinaAcademic and Professional Experience2016-present Adjunct Professor, Faculty of Health Sciences,University of Macau2009-present Professor, Department of Anatomy,University of Kansas Medical Center2008-present Investigator, Stowers Institute for Medical Research2005-2009 Associate professor, Department of Anatomy,University of Kansas Medical Center2004-2008 Associate investigator, Stowers Institute for Medical Research2002-2005 Assistant professor, Department of Anatomy,University of Kansas Medical Center2000-2003 Assistant investigator, Stowers Institute for Medical Research1996-1999 Postdoctoral fellow, Carnegie Institution of Washington/Howard Hughes Medical Institute, Baltimore, Maryland
近期论文
Representative PublicationsLu T, Wang S, Gao Y, Mao Y, Yang Z, Liu L, Song X, Ni J, Xie T. COP9-Hedgehog axis regulates the function of the germline stem cell progeny differentiation niche in the Drosophila Ovary. Development. 2015 Dec 15;142(24):4242-52. doi: 10.1242/dev.124768.Fu Z, Geng C, Wang H, Yang Z, Weng C, Li H, Deng L, Liu L, Liu N, Ni J, Xie T. Twin promotes the maintenance and differentiation of germline stem cell lineage through modulating multiple pathways. Cell Reports. 2015 Nov 17;13(7):1366-79. doi: 10.1016/j.celrep.2015.10.017. Epub 2015 Nov 5.Wang S, Gao Y, Song X, Ma X, Zhu X, Mao Y, Yang Z, Ni J, Li H, Malanowski KE, Anoja P, Park J, Haug J and Xie T. Wnt signaling-mediated redox regulation maintains the germ line stem cell differentiation niche. eLife. 2015; 4:e08174. DOI: 10.7554/eLife.08174.Ouyang J, Yu W, Liu J, Zhang N, Florens L, Chen J, Liu H, Washburn M, Pei D, Xie T. Cyclindependent Kinase-mediated Sox2 Phosphorylation Enhances the Ability of Sox2 to Establish the Pluripotent State. J Biol Chem. 2015; 290(37):22782-94.Pan L, Wang S, Lu T, Weng C, Song X, Park JK, Sun J, Yang ZH, Yu J, Tang H, McKearin DM, Chamovitz DA, Ni J, Xie T. Protein competition switches the function of COP9 from self-renewal to differentiation. Nature. 2014; 514(7521):233-6.Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N. A regulatory network of Drosophila germline stem cell self-renewal. Dev Cell. 2014; 28(4):459-73.Ma X, Wang S, Do T, Song X, Inaba M, Nishimoto Y, Liu LP, Gao Y, Mao Y, Li H, McDowell W, Park J, Malanowski K, Peak A, Perera A, Li H, Gaudenz K, Haug J, Yamashita Y, Lin H, Ni JQ, Xie T. Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary. PLoS One. 2014; 9(3):e90267.Wang Y, Xie T. Extracellular, stem cells and regenerative ophthalmology. J Glaucoma. 2014; 23(8 Suppl 1):S30-3.Chen S, Li H, Gaudenz K, Paulson A, Guo F, Trimble R, Peak A, Seidel C, Deng C, Furuta Y, Xie T. Defective FGF signaling causes coloboma formation and disrupts retinal neurogenesis. Cell Res. 2013; 23(2):254-73. (advance online publication 13 November 2012; doi:10.1038/cr.2012.150).Chen S, Lewallen M, Xie T. Adhesion in the stem cell niche: biological roles and regulation. Development. 2013; 140(2):255-65. (doi:10.1242/dev.083139).
