个人简历

2015-至今, 南京工业大学先进材料研究院，研究员\r
2009-2015，新加坡神经科学研究院，研究员\r
2005-2009，新加坡中央医院，研究员\r
2003-2005，汕头大学医学院，博士后\r
1998-2003，四川大学，生理学博士\r
1993-1998，山东济宁医学院，预防医学学士

研究领域

""主要从事中枢神经退行性病变的相关研究，利用细胞、线虫、果蝇、小鼠等多种模型，揭示中枢神经系统损伤的分子机制，近年来结合干细胞、化学、纳米技术，开发帕金森病等中枢性神经系统疾病的诊断及治疗新方法""""

近期论文

1.Mingrui Weng, Xue Yang, Yun Ni, Chenchen Xu, Hang Zhang, Jinjun Shao*, Nannan Shi, Chengwu Zhang*, Qiong Wu, Lin Li*, Wei Huang. (2019) Deep-red ?uorogenic probe for rapid detection of nitric oxide in Parkinson’s disease models. Sensors and Actuators B: Chemical, 283: 769-775. (Co-corresponding author).\r
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2. Qiaoqiao Ci, Jinhua Liu, Xiaofei Qin, Linqi Han, Hai Li, Haidong Yu, Kahleong Lim, Chengwu Zhang*, Lin Li*, Wei Huang. (2018) Polydopamine Dots-Based Fluorescent Nanoswitch Assay for Reversible Recognition of Glutamic Acid and Al3+ in Human Serum and Living Cell. ACS Applied Materials&Interfaces, 10: 35760-35769. (Co-corresponding author).\r
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3. Linqi Han, Riri Shi, Chenqi Xin, Qiaoqiao Ci, Jingyan Ge, Jinhua Liu, Qiong Wu, Chengwu Zhang*, Lin Li*, Wei Huang. (2018) Mitochondrial specific H2Sn fluorogenic sensor for live cell imaging by rational utilization of a dual-functional-photocage group. ACS Sensors, 3: 1622-1626. (Co-corresponding author).\r
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4. Yaqi Ding，Chenqi Xin, Chengwu Zhang*, Kah-Leong Lim, Hang Zhang, ZhenQian Fu, Lin Li* and Wei Huang. (2018) Natural Molecules from Chinese Herbs Protecting against Parkinson’s Disease via Anti-oxidative Stress. Frontiers in Aging Neuroscience, 10: artickle 246 doi: 10.3389/fnagi.2018.00246 (Co-corresponding author).\r
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5. Minrui Weng, Xiaoji Xie, Chao Liu, Kah-Leong Lim, Chengwu Zhang*, Lin Li*. (2018) The Sources of Reactive Oxygen Species and its possible role in the pathogenesis of Parkinson’s Disease. Parkinson’s Disease, doi.org/10.1155/2018/9163040 (Co-corresponding author).\r
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6. Chao Liu#, Chengwu Zhang#, Yi Zhou, Wan Qing Wong, Liying Corinne Lee, Wei Yi Ong, Sung Ok Yoon, Wanjin Hong, Xin-Yuan Fu, Tuck Wah Soong, Edward Koo, Lawrence Stanton, Kah-Leong Lim, and Zhicheng Xiao, Gavin Dawe. (2018) APP Upregulation Contributes to Retinal Ganglion Cell Degeneration via JNK3. Cell Death and Differentiation, 25: 661-676 (Co-first author).\r
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7. Chengwu Zhang, Yee Kit Tai, Bing-Han Chai, Katherine C. M. Chew, Eng-Tat Ang, Fai Tsang, Bryce W. Q. Tan, Eugenia T. E. Hong, Abu Bakar Ali Asad, Kai-Hsiang Chuang, Kah-Leong Lim*, Tuck Wah Soogn*. (2017) Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain. Neuromolecular Medicine, 19: 375-386.\r
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8. Jinhua Liu*, Duoduo Zhao, Minrui Weng, Chengwu Zhang*, Shiyu Zhang, Jixin Zhu, Yong Feng, Kaimin Shih, Wei Huang. Rational Design of Mini-size Carbon Nitride Nanosheets with Double Excitation- and pH-Dependent Fluorescence Behaviors for Two-photon Cell Imaging. (2017) CHEMISTRY – AN ASIAN JOURNAL, 12: 535-840 (Co-corresponding author).\r
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9.Chengwu Zhang, Liting Hang, Tso-Pang Yao and Kah-Leong Lim*. (2016) Parkin Regulation and Neurodegenerative Disorders. Frontiers in Aging Neuroscience, 7(article 248): 1-15.\r
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10.Chengwu Zhang, Henry Basil Adeline, Bing-Han Chai, Eugenia T.E. Hong, Chee-Hoe Ng, Kah-Leong Lim*. (2016) Pharmacological or genetic activation of Hsp70 protects against loss of parkin function. Neurodegenerative Diseases, 16: 304-316.\r
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11. Lin Li#, Chengwu Zhang#, Jing-yan Ge, Linghui Qian, Bing-Han Chai, Qing Zhu, Jun-Seok Lee, Kah-Leong Lim, and Shao-Qin Yao*. (2015) A Small-Molecular Probe for Selective Profiling and Imaging Monoamine Oxidase B Activities in Models of Parkinson’s Disease. Angew. Chem. Int. Ed, 54, 10821–10825 (Co-first author).\r
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12. Lin Li#, Chengwu Zhang#, Grace Y.J. Chen, Biwei Zhu, Chou Chai, Qing-Hua Xu, Eng-King Tan, Qing Zhu, Kah-Leong Lim*, Shao-Qin Yao*. (2014) A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson's disease models.” Nature Communications, 5: 3276 (Co-first author).